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What is Weight Loss Resistance, and Could It Be the Reason You Can’t Lose Weight?

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What is Weight Loss Resistance, and Could It Be the Reason You Can’t Lose Weight?

What is Weight Loss Resistance, and Could It Be the Reason You Can’t Lose Weight?

Learn to increase your energy, gain mental clarity, and lose weight more effectively than you ever thought possible by understanding the science behind weight loss resistance!


Are you doing everything ‘right’ like sleeping well, eating healthy, and staying active, but still not seeing the fat loss results you’re looking for? It could be due to weight loss resistance caused by mitochondrial dysfunction. Mitochondrial what…? Don’t worry, let’s break it down!

So, what exactly is weight loss resistance?

Weight loss resistance is a phenomena that occurs when someone has metabolic or hormonal imbalance that makes losing fat an uphill battle, especially because you usually don’t know what it is you’re doing wrong.

Society, social media, and other mainstream sources of ‘information’ have led us to believe that all we need to do to melt away the fat -and keep it off- is eat healthy, get enough sleep, manage our stress, and stay physically active, but that’s simply not the case. There are also many fad diets and magical pills out there that promise quick, fast, effective, and safe results, but when something seems too good to be true, it usually is. The truth is, you could be doing all the ‘right’ things and not seeing results due to underlying issues and imbalances in your body. The worst part, these imbalances are usually caused by things that are not tested for by most doctors – but more on that later.

What is the mitochondria?

You might not have heard the word ‘mitochondria’ since high school biology class, but did you know that this powerful organelle is crucial to losing fat and keeping it off. To understand the relationship between the mitochondria and fat loss, we need to understand what exactly the mitochondria does for our bodies.

Each of your cells have thousands of mitochondria and they play an important role. The mitochondria in your cells are important to your fat loss journey because they’re responsible for burning fat and carbohydrates for energy, but they can only do that when they are able to function properly.

What could cause mitochondrial dysfunction?

Things like environmental toxins, parasites, heavy metals, mold, bacteria, and other pathogens are the main culprits of mitochondrial dysfunction which leads to inflammation of the cells, also known as the cell danger response.

You don’t have to be a dirty or unhygienic person to be exposed to toxins, parasites, or bacteria; these things are everywhere and can be found in everyday things we come into contact with on a regular basis. Some people can be exposed to things in small amounts and not really be affected, while others are more sensitive and therefore feel inexplicably sick or symptomatic.

This issue is further compounded by the fact that mainstream doctors don’t typically test for toxins and most pathogens, nor do they look for parasites or radiation in the body – at least not at first. And if they’re not looking for them, they won’t find them so they will continue to remain in your body causing inflammation in your cells.

Understanding the Cell Danger Response and what it means for fat loss

Let’s start with a standard textbook definition of the cell danger response and then we’ll break it down piece by piece.

The cell danger response (CDR) is the evolutionarily conserved metabolic response that protects cells and hosts from harm. It is triggered by encounters with chemical, physical, or biological threats that exceed the cellular capacity for homeostasis.

Alright, that’s a lot of technical terminology and it probably means absolutely nothing to you, but it all boils down to this: your mitochondria are responsible for regulating the cell danger response which is what controls innate immunity and healing in your body. So, when the mitochondria in your cells are under attack by things like toxins and pathogens, they get into defense mode and this is known as the cell danger response.

This means that the mitochondria that are supposed to be burning fat for energy aren’t able to do that properly anymore because their job has changed from creating energy to asking for help! They are under attack after all.

So, what do the mitochondria do in this situation? They leave! The mitochondria begin to migrate outside of your cell which is a huge problem because they can’t do their job of burning fat for energy when they’re outside the cell walls. When the mitochondria are outside the cell walls, they release a fluorescent stained color that triggers the cells next to them and creates a rapid response to get the immune system’s signal.

This dysfunctional migration of the mitochondria is what causes weight loss resistance because your body is unable to metabolize the way it’s supposed to. The cell danger response leads to chronic illness because it inhibits your body’s ability to properly heal itself.

What can you do about it?

The only way to overcome weight loss resistance and mitochondrial dysfunction caused by toxins and pathogens is to directly address the root cause of the issue. Harmful toxins and pathogens accumulate in our bodies throughout our lives and remain in the body until they’re removed by someone who is actually looking for them, can properly identify them, and can understand how to remove them safely and for good.

Its not just about doing a detox and hoping for the best, these toxins and pathogens need to be removed in a specific order in order to get your body out of the cell danger response and that’s what we specialize in at Jack Kunkel’s Alternative Medicine

If you’re looking for an effective fat loss strategy that is evidence based and backed by scientific fact, then book a consultation today. You’ll get answers at your first appointment and leave feeling confident that you’re on the path to a healthier you!


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Dr. Jack Kunkel offers alternative medical services that provides custom and effective solutions for your body and mind by using a three-step strategic approach based on key pillars such as nutrition, exercise, and herbs & whole food supplements.