Whatever you’re doing now—whether you’re on a GLP-1, planning to stop taking it, dealing with hunger or regaining weight, or attempting to improve your blood sugar—what happens next is important.
The use of GLP-1 medications has greatly altered the way weight is lost and diabetes is managed.
For many people, they have helped reduce appetite, calm the ‘food noise’, improve blood sugar levels, and lead to considerable weight loss.
Now we’re coming across another aspect of the story.
What happens to your muscle while you’re losing weight?
What occurs when hunger comes back?
What effect does this have on your blood sugar and on your insulin response?
And perhaps most importantly:
What is the result if you reduce or discontinue the medication?
Research is now providing an answer, and that is one reason I am creating a completely new program.
The Weight-Regain Problem
One of the main concerns is not necessarily losing weight from using a GLP-1.
It is maintaining those results afterward.
In the extension study, those participants who stopped taking semaglutide regained about two-thirds of the weight they had lost earlier within one year.
Similar results have been observed with tirzepatide. When treatment was discontinued, participants regained significant weight, while those who continued treatment generally maintained or continued improving their results.
This tells us something extremely important:
We should start preparing for the period after the medication is discontinued, before it’s no longer there.
That is precisely what this new program is being designed to achieve.
Introducing the Complete GLP-1 & Metabolic Success Program
I’ve designed this program around five major metabolic situations I increasingly see in practice:
1. GLP-1 Weight-Loss Support
If you are currently on a GLP-1, your aim should not be merely to decrease the number on the scale.
Our aim should be to promote fat loss while preserving lean muscle, ensure adequate nutrition and protein intake, support energy levels, and enhance the basic metabolic environment.
2. Support for transitioning between GLP-1 drugs and for preventing weight regain
This is perhaps the most important—and most overlooked—item.
When the prescribing clinician decides to reduce or stop GLP-1 therapy, appetite and food noise may come back.
Rather than waiting for weight to return, we’ll develop a transition plan to promote appetite control, muscle retention, blood sugar management, and long-term weight maintenance.
3. Support for appetite and abdominal fat
You don’t need a GLP-1 to get the benefits of this method.
Continuous hunger, cravings, difficulty feeling satisfied after eating, and increased central or abdominal fat are all signs we should look more closely at the signals the body sends about metabolism.
The goal isn’t just to eat less.
It’s about understanding why your body keeps asking for more.
4. Support for Blood Sugar, Insulin and A1C
The program will also be designed for individuals who are struggling with prediabetic blood-sugar levels, insulin resistance, glucose spikes after meals, or high A1C values.
We’ll look at more than just fasting glucose.
What happens after you eat can show us a great deal about how efficiently your body processes carbohydrates, fats, and the energy it receives.
Which is why meal-level metabolic support will form an important part of the program.
5. Long-term metabolic health and maintenance
Well, once you’ve achieved your objective, what then happens?
You shouldn’t have to spend the rest of your life “dieting.”
The ultimate objective is to develop a sustainable strategy that supports healthy appetite, lean muscle, blood-sugar stability, metabolic resilience, and long-term weight maintenance.
Because Your Body Sends Signals—and Order Matters
This is where my Foundational Signals™ method sets this program apart.
No single hormone, medication, supplement, or diet can regulate weight.
We need to look at the signals influencing your metabolism:
Nutrition, muscle, blood sugar, hormones, gut function, mitochondrial health, and nutrient status, together with environmental stressors.
But here’s something I’ve learned after decades of working with difficult metabolic cases:
Locating the problem isn’t enough; the order matters.
Two people can have the exact same symptoms and requirements. That is why, rather than simply adding another diet, supplement, peptide, or protocol, we determine what your body is struggling with and what to tackle first.
Optimize → Transition → Thrive
This philosophy underlies the whole program.
Optimize. Protect your health and guard your muscles when using GLP-1 therapy.
Transition. If you and your prescribing clinician consider it the right time to reduce or stop the medication, it makes sense to transition.
Thrive. Achieve success by establishing the metabolic foundation needed to keep your results for the long term.
Join the Priority Waitlist
I am starting a limited Priority Waitlist for the Complete GLP-1 & Metabolic Success Program.
Waitlist members will get first access when enrollment opens, plus program updates and special introductory/founding-member pricing.
→ Email Joe Coco at joe@jackkunkel.com
If this isn’t something you need personally, but you know someone using a GLP-1, planning to come off one, struggling with weight regain, or trying to improve their metabolic health, please forward this email to them. They can also join the Priority Waitlist.

